Neurons (green) and astrocytes (magenta) erupt from this confocal image of a differentiated clone of mouse neural stem cells. These are multipotent stem cells capable of differentiating into neurons, astrocytes, or oligodendrocytes. Researchers in the lab of John Engelhardt, PhD, UI professor and department executive officer of anatomy and cell biology, study the mechanisms regulating expansion and differentiation of neural stem cells. Altering these mechanisms can promote expansion of neural stem cells and shift their differentiation toward neurons after stroke. These effects improved survival and recovery in an animal model of stroke. The image comes from Weam Shahin, MD, PhD, a postdoctoral research scholar in the Engelhardt lab.