Link: University of Iowa

Archive for March, 2015

John Pryor wins the Clarence Berg Award

Monday, March 16th, 2015

John Pryor, a 2012 PhD with Dr. Todd Washington, has been named the winner of the 2014 Clarence Berg Award. The Berg Award is given biennially in honor of our former Professor Clarence P. Berg to the graduate student who demonstrates “scholarship, integrity, cooperativeness, consideration and a willingness to help others.” Dr. Pryor was an American Heart Association-funded graduate student who focused on the role of replication accessory factors in promoting translesion DNA synthesis.

Previously, John was named the winner of the 2013 Subramanian Award for best PhD thesis in the Department of Biochemistry.  John is a Lineberger Cancer Center Postdoctoral Fellow in Dale Ramsden’s laboratory at the University of North Carolina. His postdoctoral work will focus on the mechanism of DNA double-strand break repair by the non-homologous end-joining pathway. Congratulations to Dr. Pryor!

Karina Kruth wins the Subramanian Thesis Award

Monday, March 16th, 2015

Karina Kruth, who completed her PhD with Dr. Peter Rubenstein, has been named the 2014 Subramanian Award for best PhD thesis in the Department of Biochemistry. Karina is a postdoctoral scholar in Dr. Miles Pufall’s laboratory at the University of Iowa, Department of Biochemistry. Her postdoctoral work will focus on the glucocorticoid receptor structure and resistance to glucocorticoid treatment in Acute Lymphoblastic Leukemia.

Karina is the 21st winner of the Subramanian Award, which is made possible by a gift from Dr. Alap Subramanian, a 1964 PhD from the department, who parlayed his training with the late George Kalnitsky, (and with Irving Klotz at Northwestern and both Bernard Davis and Herman Kalckar at Harvard Medical School), into a highly successful career at the Max-Planck-Institut. Our deepest thanks to Dr. Subramanian and our heartiest congratulations to Dr. Kruth.

Brandon Davies awarded a 2015 Carver Trust Grant

Friday, March 13th, 2015

Davies 200x300Dr. Brandon Davies has been awarded a 2015 Carver Trust Medical Research Initiative Grant for his project entitled “Understanding the Roles of ANGPATL in Triglyceride Metabolism.”

Three members of the angiopoietin-like (ANGPTL) family–ANGPTL3, ANGPTL4, and ANGPTL8, are important regulators of triglyceride metabolism. Each is thought the influence the activity of lipoprotein lipase, the enzyme responsible for processing circulating triglycerides. Dr. Davies’ goal is to understand how ANGPTL3, ANGPTL4, and ANGPTL8 interact with each other and with LPL.

Congratulations, Dr. Davies!

Eric Taylor receives new R01

Friday, March 13th, 2015

taylor_D3A3324Dr. Eric Taylor was recently awarded a new NIH R01 entitled “Regulation of Hepatic Gluconeogenesis by the Mitochondrial Pyruvate Carrier.” Dr. Taylor has been awarded $250,000/year for five years.

High blood sugar is a defining feature of Type 2 Diabetes that is responsible for many of its complications. A major cause of high blood sugar is excessive glucose production by the liver. One of the liver’s most preferred building blocks for glucose is a molecule called pyruvate. To build glucose, pyruvate must be transported to the inside of mitochondria, the energy-producing hub of the cell, by a specialized portal named the Mitochondrial Pyruvate Carrier (MPC). Thus, the MPC is potentially a critical point in metabolism for controlling glucose production. Dr. Taylor’s goals are to determine the molecular mechanisms regulating MPC function and whether inhibiting MPC activity will therapeutically decrease elevated blood sugar levels in Type 2 Diabetes

Congratulations, Dr. Taylor!

Grant Young featured on IowaNow’s “Student Experience”

Friday, March 13th, 2015

Grant Young, an undergraduate major in the Wallrath laboratory,was recently interviewed for the IowaNow’s “Student Experience,” where they discuss Grant’s achievements  inside and outside the laboratory. Dr. Wallrath states, “He takes his academic life very seriously, he thinks hard about his career goals and his future, and he also really understands the science behind what he’s doing in the laboratory, and that’s a real key to bringing that picture complete.” She continues, “Being able to complete projects to the point of where they’re published is a huge thing to be able to do as an undergraduate.”

Biochemistry Students Invited to Phi Beta Kappa Honor Society

Wednesday, March 11th, 2015

Congratulations to the following Biochemistry students, who were invited to accept membership in the Phi Beta Kappa Honor Society!

Alexander Hjelmaas, Nicoll Manhica, Sarah Mayer, Sarah Misselhorn, Samuel Mueting, Michael Turek, Xin Xu, and Grant Young.

The Phi Beta Kappa Society is the oldest and most prestigious undergraduate honors organization in the United States.