Link: University of Iowa

Department announces hiring of Dr. Brandon Davies

The Department of Biochemistry, the Fraternal Order of Eagles Diabetes Research Center (FOEDRC), and the Obesity Initiative (OI) are pleased to announce the 2nd faculty hire from the diabetes and obesity search initiated in September 2011.

Dr. Brandon Davies is a 2000 BA from University of Utah and a 2005 PhD from University of California, Berkeley. At Berkeley, in Jasper Rine’s laboratory, he uncovered a role for sterol levels in oxygen sensing and adaptation to hypoxia in Saccharomyces cerevisiae. His work was published in first author papers in Genetics and Molecular& Cellular Biology.

In 2006, he moved to Stephen Young’s laboratory in the Cellular and Molecular Cardiology Unit of the Department of Medicine at University of California, Los Angeles. Dr. Davies has thrived in this environment, producing a body of 23 original research papers (4 first author), and 8 reviews (4 first author). His work has made a high impact in two areas. First, he has used engineered forms of Lamin A to dissect the significance of the post-translational farnesylation and proteolysis of prelamin A and how defects in these processing steps contribute to laminopathies. Second, he performed groundbreaking work on a molecule termed GPIHBP1, which he discovered is essential to transport lipoprotein lipase from muscle and fat cells into the bloodstream. Dr. Davies’s major discoveries have been published in first author articles in Cell Metabolism. His work is highly cited and original.

In the course of Dr. Davies’s post-doctoral fellowship, he has given invited or awarded presentations at four national meetings, won numerous awards at UCLA, and obtained an American Heart Association (AHA) post-doctoral fellowship award. He is now the PI of a $280,000 (direct cost) AHA Scientist Development Grant that he will bring to the University of Iowa. The goal of his research laboratory will be to exploit the role of GPIHBP1 to dissect regulation of lipid transport and utilization in health and in diseases of energy imbalance such as type 2 diabetes and the metabolic syndrome.

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