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Archive for the ‘Michael Lenardo’ Category

Department fetes Plapp and Donelson

Saturday, September 3rd, 2011

Biochemists gathered on August 29 at Chef’s Table in Iowa City to celebrate the transitions to emeritus of Bryce Plapp and John Donelson, who contributed a combined 77 years of service to the Department. ¬†Charles Brenner read a commendation letter written by Samuel Zakhari of the National Institute of Alcohol Abuse and Alcoholism on the 40th anniversary of Bryce’s first NIH grant, commending him for his “remarkably productive career in alcohol research, particularly on a central enzyme of alcohol metabolism, alcohol dehydrogenase.” Zakhari’s letter referred to Bryce’s scientific heritage as a senior fellow with Nobelists Stein and Moore and recognized his “extraordinary commitment to mentoring young research scientists.”

James Hartley and Michael Lenardo, former post-doctoral fellows in the Donelson lab, made the trip from the NIH where they now direct laboratories. This gave John the opportunity to muse on James’s DNA sequencing project, the yeast 2 micron circle. Michael brought a commendation letter from Louis Miller of the National Institute of Allergy and Infectious Diseases, who wrote that “you were always the leader in the world in molecular biology of Trypanosomes.” He also read from two published recollections of John’s post-doctoral adviser Frederick Sanger (Nobel 1958 and Nobel 1980) on John’s contribution to the development of DNA sequencing.

Former Iowa post-doc Michael Lenardo identifies magnesium as second messenger

Friday, August 19th, 2011

Michael Lenardo, Chief of the Molecular Development of the Immune System section at the National Institute of Allergy and Infectious Diseases, a former post-doc with John Donelson has a major paper in Nature discovering a second messenger role for magnesium ion in antigen receptor and growth factor receptor signaling. This discovery comes close on the heels of other major papers in PNAS, Immunity and Nature Immunology.