Link: University of Iowa

Archive for the ‘Zhen Xu’ Category

Elizabeth Boehm and Zhen Xu Earn PhD Summer 2016

Wednesday, August 24th, 2016

Boehm, ElizabethElizabeth Boehm, a Biochemistry PhD student mentored by Dr. Todd Washington, received her PhD on August 5, 2016. Elizabeth’s thesis is entitled, ” The regulation of translesion synthesis through the binding and activation of polymerases by PCNA”. Elizabeth has accepted a position as a postdoctoral positionĀ at Harvard Medical School in Johannes Walter’s lab to study DNA replication and repair inĀ Xenopus laevis.

 

Xu, Zhen

Zhen Xu, a Biochemistry PhD student mentored by Dr. Ernesto Fuentes, received his PhD on August 5, 2016. Zhen’s thesis is entitled, “Auto-inhibition mechanism of the guanine nucleotide exchange factor TIAM1.” Zhen has accepted a postdoctoral position at the University of Iowa in Ernesto Fuentes’ lab.

Congrats Elizabeth and Zhen!

Fuentes group featured on the March 5 cover of Structure

Thursday, March 21st, 2013

Dr. Ernie Fuentes was senior author on a study on the Tiam1 PDZ domain bound with (phos) syndecan1 (SDC1) ligands. The x-ray crystallographic studies show how the Tiam1 PDZ domain preferentially interacts with a subset of SDC proteins, while NMR studies indicate the dynamic decoupling stimulated by SDC1 phosphorylation. The findings reveal a phosphorylation-based regulation mechanism on the selection of SDC ineratome. The paper was published in the March 5 issue of Structure, along with a cover image that illustrates the syndecan intractome and how a PDZ domain selects its partner protein. The paper is also a recommended article on Faculty of 1000 Prime, and is co-authored by current and former members of the Fuentes lab including current graduate students Xu Liu (first author) and Zhen Xu, former graduate student Tyson Shepherd, and Ann Murray.

Department to welcome 9 new graduate students

Wednesday, April 21st, 2010

The graduate recruiting season has come to a successful close with nine students committing to the Department of Biochemistry.

Casey Andrews hails from Spring Lake, Michigan and attended Grant Valley State University. An inorganic chemist by training, he has a primary research interest in carcinogenesis.

John Brogie is from Oskaloosa, Iowa and attended Wayne State College. He has conducted research on biofuel production from Clostridium acetobutylicum and plans to do high tech research with awesome facilities.

Yingyue (Annie) Li is from Cangzhou City in China. At Hebei University, she cloned odorant receptor genes from snail antenna. She remarked in her application that she is eager to apply her inquisitiveness, research ability and determination to her PhD at Iowa.

Sufang Mao is from Guangzhou, China and attended South China Agricultural University, where she worked on natural products from the mushroom, Cordyceps militaris. Her main interests are allosteric regulation, large scale modeling and structural biology.

Yuan Pan is from Shenzhen, China and attended Hong Kong University of Science and Technology. She has conducted research on microtubule plus-end protein EB1 and will pursue her PhD in an area of fundamental biochemistry.

Nicole Vanderpool is from Mason City, Illinois and attended University of Illinois, Springfield. She conducted undergraduate research on the relationship between iron availability and nitrogen consumption in soil microbes. Going into graduate school, she has a strong interest in chromatin.

Om Kumar Shrestha is from Bharatpur, Nepal and attended Monmouth College, where he did NMR on enzymatic digestion of cellulosic biomass and engineered E. coli to resist ethanol. His interest in biochemistry was inspired by research mentors. He therefore wants to conduct research and continue the chain of mentorship to the next generation.

Zhen Xu is from Hefei, China and attended University of Science and Technology of China, where he did structural biology research. He enters graduate school with a strong interest in membrane proteins.

Chaoqun Zheng is from Beijing, China and attended Shanghai Jiaotong University, where he worked on C. elegans genomics. He enters graduate school with a strong interest in epigenetics, function of tumor suppressor genes, and metabolism.

Watch for the arrival of this class of graduate students this summer!