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Archive for the ‘Shyamal Subramanyam’ Category
Dr. Maria Spies laboratory recently published an Proceedings of National Academy of Sciences article entitled “Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through altered nucleoprotein filament dynamics.” In this article the Spies laboratory addressed the regulation of the homologous genetic recombination, an enigmatic cellular mechanism responsible for the stability of our genomes and accurate repair of the most deleterious DNA damage. They combined the tools of biochemistry, chemical biology and single-molecule biophysics to determine the mechanism by which c-ABL kinase (and its oncogenic counterpart BCR-ABL) enhances the activity of human RAD51 recombinase, which catalyzes the central step in homologous recombination. Recent PhD, Shyamal Subramanyam, was first author of this work, which was a cornerstone of his dissertation.
The 2012 Biochemistry Retreat, organized by Lori Wallrath, Todd Washington, John Brogie and Julie Lueth, was held on Saturday, August 24 at the Coralville Public Library. Short talks were given in the morning by Ernesto Fuentes, Karina Kruth (Rubenstein lab), Shyamal Subramanyam (M. Spies lab), Michael Schnieders, Brandon Davies, Charles Brenner, Jessica Maiers (DeMali lab) and Adrian Elcock. After lunch, talks were given by Maria Spies, David Price and Eric Taylor.
The poster session featured 29 posters. Eight total awards were given in three categories: in the undergraduate division, James Bullard (Geyer lab), Melinda Martin (Geyer lab) and Alexander Greiner (Rubenstein lab) won first, second and third, respectively; in the Postdoc/Research Assistant/Associate category, William Jones (M. Spies lab), Jiannan Guo (Price lab) and Christy Mei (Brenner lab) won first, second and third, respectively.
Two Lois Bigger Gehring Awards were given to support graduate student travel to research conferences. Xiaowen Sun (DeMali lab) and Yuan Pan (Baker lab) each won this award for best poster in the graduate student category.
Thanks to everyone for participating.
Next year the retreat will be centered around the Department’s 65th Birthday. Be sure to save the dates: August 23-25, 2013.