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Archive for the ‘Lawrence Gray’ Category

Taylor Lab publish in the Journal of Biological Chemistry

Friday, February 12th, 2016

Drs. Larry Gray and Adam Rauckhorst of the Taylor Laboratory recently published an article entitled “A Method for MultiplexedMeasurement of Mitochondrial Pyruvate Carrier Activity,” in the Journal of Biological Chemistry. Mitochondrial pyruvate uptake is a central metabolic decision that affects cellular energy production, carbon flux through multiple biosynthetic pathways, and commitment to cellular fate. The recent discovery of the genes encoding the mitochondrial pyruvate carrier (MPC), the protein complex that conducts pyruvate into the mitochondrial matrix, has invigorated studies on the regulation of mitochondrial pyruvate uptake. An effective activity assay is important for these efforts but previous methods were constrained by high sample requirements and a single replicate-based workflow. Drs. Gray and Rauckhorst co-developed a 96-well scaled assay that enables much greater throughput with substantially decreased mitochondrial sample requirements. They applied this method to provide the first report on the Km and Vmax of the mouse liver MPC. They expect this assay will be useful for understanding the regulation of MPC activity under diverse physiological conditions in health and disease.

Larry Gray receives Most Outstanding Entry for the CCOM Health Sciences Research Week Poster Competition

Thursday, April 23rd, 2015

Larry GrayDr. Larry Gray, a postdoc in the Taylor laboratory, received a a most outstanding entry for the Carver College of Medicine Health Sciences Research Week poster competition. Larry was recognized at the Research Week awards reception on Thursday, April 23, 2015.

Congratulations, Larry!

Larry Gray wins the Subramanian Thesis Award

Thursday, September 20th, 2012

Lawrence Gray, who recently completed his PhD with Sharam Khademi, has been named the winner of the 2012 Subramanian Award for best PhD thesis in the Department of Biochemistry. Larry is currently pursuing post-doctoral studies with Dr. Eric Taylor.

Larry is the 19th winner of the Subramanian Award, which is made possible by a gift from Dr. Alap Subramanian, a 1964 PhD from the department, who parlayed his training with the late George Kalnitsky, (and with Irving Klotz at Northwestern and both Bernard Davis and Herman Kalckar at Harvard Medical School), into a highly successful career at the Max-Planck-Institut. Our deepest thanks to Dr. Subramanian and our heartiest congratulations to Dr. Gray.

Larry Gray defends PhD thesis

Friday, July 27th, 2012

Lawrence Gray, a PhD student mentored by Sharam Khademi, has successfully defended his thesis, entitled “Detailed characterization of the urea channel UreI from Helicobacter pylori.” After graduation Larry will join the laboratory of Dr. Eric Taylor as a post-doc researcher. He plans to pursue a  career in academia. Congratulations to Larry!

Biochemistry well-represented at Biophysical Society annual meeting

Saturday, March 3rd, 2012

Iowa Biochemistry was well-represented this past week at the annual meeting of the Biophysical Society. Dr. Ernie Fuentes gave a talk at the meeting. Larry Gray, a graduate student in the Khademi lab, was awarded a Student Research Award from the poster competition on Monday, for his work on the pH-dependent conduction of urea through the UreI channel in the ulcer-causing bacteria Helicobacter pylori.

Also in attendance at this meeting were Dr. Madeline Shea and her lab and Dr. Kris DeMali and her lab.

Highlights of the Annual Retreat

Thursday, September 1st, 2011

The 2011 Biochemistry Annual Retreat, chaired by Lori Wallrath and Lacy Barton, was held on Saturday, August 27 at the Coralville Public Library. Short talks were given in the morning by Kris DeMali, Larry Gray, Lacy Barton, Daniel Weeks,  Todd Washington, Xu Liu, Aaron Ver Heul and Madeline Shea. After lunch, talks were given by Marc Wold, Charles Brenner and Miles Pufall .

The poster session featured 31 posters. Seven awards were given in two divisions. Ashley Angell from the DeMali laboratory and Kristen Syring from the Wallrath laboratory won first and second place in the undergraduate division. In the post-doctoral and staff division, Rebecca Fagan from the Brenner laboratory took first place.  There was a three way tie for second place between Jennifer Bays from the DeMali laboratory, Brett Waite from the Shea laboratory, and Kuo-Kuang Wen from the Rubenstein laboratory.

Two Lois Bigger Gehring Awards  were given to support graduate student travel to research conferences. These awards were given to John Pryor from the Washington laboratory and Alexey Soshnev from the Geyer laboratory.

Thanks to everyone for participating.

Highlights of the Annual Retreat

Monday, August 30th, 2010

The Brechler Press Box of Kinnick Stadium was abuzz with Biochemists on saturday for an all-department retreat. As Hawkeye football players ran drills on the field, retreat organizer David Price asked the ~100 attendees to take seats facing the field for a special announcement. Eyes turned toward the jumbotron above the south endzone for a powerpoint tribute to the department, featuring faculty photos and a few candid shots.

Short talks were giving in the morning by Charles Brenner, Pamela Geyer, Ernesto Fuentes, Lori Wallrath and Peter Rubenstein. After lunch, short talks were given by David Price, Sheila Baker, Adrian Elcock and the department’s 2011 faculty recruit, Miles Pufall.

The poster session featured 32 posters. Eight poster awards were given in 4 divisions. Rini Kasinathan from the Geyer laboratory earned the undergraduate prize. Sarah Bergeron from the Rubenstein laboratory, Lawrence Gray from the Khademi laboratory, and Tyson Shepherd from the Fuentes laboratory won first, second and third places in the graduate student division. Jeffrey Cooper from the Price laboratory took honors among research assistants. Finally, Rebecca Fagan from the Khademi laboratory, George Dialynas from the Wallrath laboratory, and Kuo-Kuang Wen from the Rubenstein laboratory won first, second and third places in the post-doctoral division.

The retreat was clearly an energizing event for first year graduate students in attendance. Thanks to all of the presenters and to everyone for participating.

Dr. Lois Bigger Gehring Awardees

Tuesday, September 22nd, 2009

Lois Bigger Gehring, a great friend of the Department of Biochemistry, has created an endowment for the Department to support graduate students.   (more…)