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Archive for the ‘John Brogie’ Category

Price lab featured on the August cover of Molecular Cell

Thursday, August 20th, 2015

MOLCEL_59_4.c1.inddDavid Price‘s lab was featured on the August 20 cover of Molecular Cell. The article entitled “THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing,”shows how a Cdk7 inhibitor, THZ1, dramatically impacts CTD phosphorylation, co-transcriptional capping, pausing, and P-TEFb-dependent productive elongation by disrupting an ordered exchange of factors after initiation. These results provide mechanistic insights into the anti-proliferative and super-enhancer-selective effects of THZ1 seen by others. Kyle Nilson, (Molecular and Cellular Biology Graduate Student in the Price Lab) was first author of this work. John Brogie (Biochemistry Graduate Student), Michael Turek (Biochemistry Undergraduate Major), and Jiannan Guo (Former Biochemistry Postdoc, Price Lab) also contributed to this work. The cover design by Kyle Nilson features and experiment “performed” by Nicholas Mullen (Biochemistry Undergraduate Major).

The article is also featured in a preview by Drs. Frédéric Coin and Jean-Marc Egly entitiled “Revisiting the Function of CDK7 in Transcription by Virtue of a Recently Described TFIIH Kinase Inhibitor.”

Congratulations Price Lab!!

Faculty featured in Fall meetings and symposiums

Friday, September 21st, 2012

Lori Wallrath gave an oral presentation at the Cold Spring Harbor Symposium ‘Dynamic Organization of Nuclear Function’ (Sept 27 – Oct 1) held in Cold Spring Harbor, NY. Her talk was titled “Connections between lamins and genes involved in detoxification and neuromuscular junction function”.

David Price delivered a keynote address at the LARP Society Meeting in Banyuls Sur Mar, France on “The role of LARP7 and the 7SKsnRNP in regulating P-TEFb.” Biochemistry graduate student, John Brogie, who also attended the meeting and presented a poster, was elected to be the Graduate Student Representitive to the LARP Society.

Nancy Stellwagen gave an invited talk and chaired a discussion session at the 13th International Symposium on Colloidal and Molecular Electrooptics, held Sept. 2-5 in Ghent, Belgium. Nancy will also give an invited talk and chair a discussion session at the 19th International Symposium on Electro- and Liquid Phase-separation Techniques, to be held from Sept. 30 to Oct. 3 in Baltimore, MD and the AES Electrophoresis Society annual meeting in Pittsburgh Oct. 29-31. At the AES Society meeting, she will be given the 2012 achievement award for contributions to the field electrophoretic separations, as well as service to the society. The award session has been named in her honor.

Highlights of the third annual Biochemistry Retreat

Monday, August 27th, 2012

The 2012 Biochemistry Retreat, organized by Lori Wallrath, Todd Washington, John Brogie and Julie Lueth, was held on Saturday, August 24 at the Coralville Public Library. Short talks were given in the morning by Ernesto Fuentes, Karina Kruth (Rubenstein lab), Shyamal Subramanyam (M. Spies lab), Michael Schnieders, Brandon Davies, Charles Brenner, Jessica Maiers (DeMali lab) and Adrian Elcock. After lunch, talks were given by Maria Spies, David Price and Eric Taylor.

The poster session featured 29 posters. Eight total awards were given in three categories: in the undergraduate division, James Bullard (Geyer lab), Melinda Martin (Geyer lab) and Alexander Greiner (Rubenstein lab) won first, second and third, respectively; in the Postdoc/Research Assistant/Associate category, William Jones (M. Spies lab), Jiannan Guo (Price lab) and Christy Mei (Brenner lab) won first, second and third, respectively.

Two Lois Bigger Gehring Awards were given to support graduate student travel to research conferences. Xiaowen Sun (DeMali lab) and Yuan Pan (Baker lab) each won this award for best poster in the graduate student category.

Thanks to everyone for participating.

Next year the retreat will be centered around the Department’s 65th Birthday. Be sure to save the dates: August 23-25, 2013.

Department to welcome 9 new graduate students

Wednesday, April 21st, 2010

The graduate recruiting season has come to a successful close with nine students committing to the Department of Biochemistry.

Casey Andrews hails from Spring Lake, Michigan and attended Grant Valley State University. An inorganic chemist by training, he has a primary research interest in carcinogenesis.

John Brogie is from Oskaloosa, Iowa and attended Wayne State College. He has conducted research on biofuel production from Clostridium acetobutylicum and plans to do high tech research with awesome facilities.

Yingyue (Annie) Li is from Cangzhou City in China. At Hebei University, she cloned odorant receptor genes from snail antenna. She remarked in her application that she is eager to apply her inquisitiveness, research ability and determination to her PhD at Iowa.

Sufang Mao is from Guangzhou, China and attended South China Agricultural University, where she worked on natural products from the mushroom, Cordyceps militaris. Her main interests are allosteric regulation, large scale modeling and structural biology.

Yuan Pan is from Shenzhen, China and attended Hong Kong University of Science and Technology. She has conducted research on microtubule plus-end protein EB1 and will pursue her PhD in an area of fundamental biochemistry.

Nicole Vanderpool is from Mason City, Illinois and attended University of Illinois, Springfield. She conducted undergraduate research on the relationship between iron availability and nitrogen consumption in soil microbes. Going into graduate school, she has a strong interest in chromatin.

Om Kumar Shrestha is from Bharatpur, Nepal and attended Monmouth College, where he did NMR on enzymatic digestion of cellulosic biomass and engineered E. coli to resist ethanol. His interest in biochemistry was inspired by research mentors. He therefore wants to conduct research and continue the chain of mentorship to the next generation.

Zhen Xu is from Hefei, China and attended University of Science and Technology of China, where he did structural biology research. He enters graduate school with a strong interest in membrane proteins.

Chaoqun Zheng is from Beijing, China and attended Shanghai Jiaotong University, where he worked on C. elegans genomics. He enters graduate school with a strong interest in epigenetics, function of tumor suppressor genes, and metabolism.

Watch for the arrival of this class of graduate students this summer!