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Archive for the ‘graduate students’ Category

Hannah Campbell awarded the People’s Choice Award for Three Minute Thesis challenge

Monday, November 5th, 2018

Hannah Campbell, a graduate student in the DeMali Laboratory, was selected as one of nine finalist for the The University of Iowa’s fifth Three Minute Thesis competition, which challenges graduate students to clearly and concisely articulate complex research to non-specialist audiences.  Hannah was awarded the People’s Choice Award, selected by audience ballot, for her presentation entitled, “Cells that work together, stay together.” Congratulations, Hannah!

Samuel Trammell receives the 2018 Marion Dave Francis Innovator Award

Wednesday, September 5th, 2018

Dr. Samuel Trammell, a 2016 Genetics PhD with Dr. Charles Brenner, received the 2018 Marion Dave Francis Innovator Award which recognizes a PhD student whose research has demonstrated their singular personal initiative, creativity, and resulting continuous discovery, as exemplified by Dr. Francis. Dr. Trammell’s PhD work represents a quantum leap in analytical chemistry of the nicotinamide adenine dinucleotide (NAD) metabolome. His body of work greatly advanced methodology and our understanding of regulation and dysregulation of NAD metabolism in health and disease. Sam is currently a postdoctoral fellow in the laboratory of Dr. Matthew Gillium at the University of Copenhagen. Congratulations, Dr. Trammell!

Jennifer Bays awarded the 2018 Subramanian Thesis and 2018 Clarence Berg Awards

Wednesday, September 5th, 2018

Dr. Jennifer Bays, a 2017 PhD with Dr. Kris DeMali, has been named the winner of the 2018 Subramanian Award for best PhD thesis in the Department of Biochemistry.  Dr. Bays’ thesis was entitled “Mechanisms of E-cadherin Mechanotransduction.” Jennifer is the 23nd winner of the Subramanian Award, which is made possible by a gift from Dr. Alap Subramanian, a 1964 PhD from the department, who parlayed his training with the late George Kalnitsky, (and with Irving Klotz at Northwestern and both Bernard Davis and Herman Kalckar at Harvard Medical School), into a highly successful career at the Max-Planck-Institut.

Jennifer was also named the winner of the 2018 Clarence Berg Award. The Berg Award is given biennially in honor of our former Professor Clarence P. Berg to the graduate student who demonstrates “scholarship, integrity, cooperativeness, consideration and a willingness to help others.” Clarence P. Berg, an internationally known amino acid biochemist who was a member of the department for 36 years (1932-1968). Dr. Berg is well known as the author of the 1980 book, “The University of Iowa and Biochemistry from their Beginnings.”

Jennifer is currently a postdoctoral fellow in Dr. Christopher Chen’s laboratory at Boston University. Congratulations, Dr. Bays!

Highlights of the 9th Annual Biochemistry Retreat and 70th Anniversary

Wednesday, August 29th, 2018

Over 115 faculty, graduate students, postdoctoral fellows, research staff members, undergraduates, and alumni attended the Department of Biochemistry’s 9th Annual Retreat and 70th Anniversary Celebration on Saturday, August 25, 2018, at the newly rebuilt  Hancher Auditorium.

Invited oral presentations included:

Junmin Peng, PhD., Professor, Departments of Structural Biology and Developmental Neurobiology, and Director of Center for Proteomics and Metabolomics, St. Jude Children’s Research Hospital
Title: Omics-based systems biology of human disease
Dr. Peng was a former graduate student in Dr. David Price’s lab, obtaining a PhD in Biochemistry in 1999.

Lois Weisman, PhD, Professor of Cell and Developmental Biology, Life Sciences Institute, University of Michigan
Title: From yeast to humans: Insights into myosin V based transport and phosphoinositide signaling
Dr. Weisman joined the University of Iowa, Department of Biochemistry in 1993.  In 2005, Dr. Weisman moved to her current position at the University of Michigan.

James Kranz, PhD, Director, Drug Product Development, Kiniksa Pharmaceuticals
Title: Biochemistry essentials and biopharmaceutical development: Everything I need to know I first learned from Dryer & Lata “Experimental Biochemistry”
Dr. Kranz received a B.S. in Biochemistry with Honors from the University of Iowa under the mentorship of Dr. Madeline Shea.

This event also included a panel discussion with current and former Department Heads:

Charles Brenner, PhD (2009 – present)
Arthur Spector, MD (1996 – 1998)
Alan Goodridge, PhD (1987 – 1996)

The retreat featured 39 poster presentations.  Winners of the poster presentations were (left to right below):


1st place:  Hannah Campbell (DeMali Lab), Force-induced apoptosis and the mechanoprotective role of PAK2
2nd place: Alicia Ortiz (DeMali Lab), Investigating Metabolic Changes in Response to Force on E-cadherin
3rd place:  Christopher Ball (Price Lab), Human Cytomegalovirus IE2 Differentially Modulates Transcription of Select Viral Transcription Units during Late Infection
4th place:  Kelli Sylvers (Davies Lab), Characterizing the interactions between ANGPTL3, ANGPLT8, and endothelial lipase

2017 Biochemistry Newsletter now available

Thursday, November 16th, 2017

The 2017 Biochemistry @ Iowa newsletter is hot off the presses and available for download. Alumni and friends should receive a hard copy in the mail this week. If you would like to be added to our mailing list, please send your contact information to biochem@uiowa.edu. While you are at it, feel free to send us your news and updates! Previous newsletters are also available online.

Elizabeth Boehm receives 2017 Subramanian Thesis Award

Thursday, August 31st, 2017

Elizabeth Boehm, who completed her PhD with Dr. M. Todd Washington, has been awarded the 2017 Subramanian Award for best PhD thesis in the Department of Biochemistry. Dr. Boehm’s thesis was entitled “The regulation of translesion synthesis through binding and activation of polymerases by PCNA.” Elizabeth received her PhD in June 2016 and is currently a postdoctoral fellow in the lab of Johannes Walter at Harvard Medical School.

Elizabeth is the 22nd winner of the Subramanian Award, which is made possible by a gift from Dr. Alap Subramanian, a 1964 PhD from the department, who parlayed his training with the late George Kalnitsky, (and with Irving Klotz at Northwestern and both Bernard Davis and Herman Kalckar at Harvard Medical School), into a highly successful career at the Max-Planck-Institut. Our deepest thanks to Dr. Subramanian and our heartiest congratulations to Dr. Boehm.

Please visit our website for a complete list of previous winners of the Subramanian Award.

Samuel Trammell receives special Graduate Deans’ Distinguished Dissertation Award

Thursday, July 13th, 2017

Dr. Samuel Trammell, a 2016 Genetics PhD with Dr. Charles Brenner, is the recipient of a Graduate Deans’ Distinguished Dissertation Award for his dissertation entitled “Novel NAD+ Metabolomics Technologies and Their Applications to Nicotinamide Riboside Interventions.” The Graduate Deans’ Distinguished Dissertation Award is made only occasionally and recognizes exceptionally meritorious scholarship. Dr. Trammell will be recognized at the 20th Annual James F. Jakobsen Memorial Research Conference on Saturday, March 24, 2018, at the Iowa Memorial Union. Dr. Trammell is currently a postdoctoral fellow at the University of Copenhagen with Dr. Matthew Gillium working on lipid metabolism in diabetes.

 

2017 IDT & Smith-Gehring Graduate Fellowships

Wednesday, July 5th, 2017

The IDT and Smith-Gehring Graduate Fellowships are awarded to three of the most meritorious second year Biochemistry graduate students based on academic and research achievements.

The 2017 IDT Graduate Fellows are Kelli Sylvers and Christopher Ball:

Ms. Kelli Sylvers had a productive first year in the graduate program and made significant scientific progress. Her rotation work has already contributed to one research paper. Ms. Sylvers grew up in Coon Rapids, Minnesota and graduated with a B.S in Biochemistry and a B.A in Biology from The College of St. Scholastica (Duluth, MN) in spring 2016. Ms. Sylvers is training in the laboratory of Dr. Brandon Davies. Her research involves the characterization of two circulating factors, ANGPTL3 and ANGPTL8, that regulate lipid metabolism. ANGPTL3 and ANGPTL8 form a complex that inhibits lipoprotein lipase, the enzyme responsible for delivering triglycerides from the bloodstream to tissue. ANGPTL3, and possibly ANGPTL8, can also inhibit endothelial lipase, a major regulator of HDL.  Moreover, targeting ANGPTL3 and ANGPTL8 can therapeutically lower plasma lipids, which may reduce the risk of cardiac disease. The goals of Ms. Sylvers research are to understand the interactions between ANGPTL3 and ANGPTL8, characterize the mechanisms by which they inhibit lipoprotein lipase and endothelial lipase, and to identify small molecules that can disrupt the action of ANGPTL3 and ANGPTL8 complexes.

Mr. Christopher Ball had an outstanding first year. He earned over a 4.0 average in his classes for the two semesters and performed in an exemplary manner during his three rotations. During his rotations, he got up to speed quickly in each of the three very different research environments and was able to contribute intellectually to each project. Having a good idea is easier than putting that idea into practice, but Mr. Ball is able to fully translate his imagination into experiments that work. Mr. Ball entered Dr. David Price’s lab in the Spring and has begun several projects aimed at understanding the regulation of transcription by human RNA polymerase II. He is utilizing both biochemical and molecular approaches. Key to his success is his soft spoken thoughtfulness coupled with a drive to succeed. Mr. Ball will attend the Cold Spring Harbor Lab meeting on Transcriptional Mechanisms in the Fall where he will present some of his first results demonstrating a rapid increase in transcribing RNA polymerase II in cells under oxidative stress.

The 2017 Smith-Gehring Graduate Fellow is Alicia Ortiz:

Ms. Alicia Ortiz joined the Biochemistry Department in the Fall of 2016 after having been actively engaged in microbiology research at University of Nebraska at Lincoln.  Upon her recruitment to the University of Iowa, Alicia was named an Alfred P. Sloan Scholar, a fellowship awarded to promote the doctoral training of deserving US citizens from minority backgrounds.  As a first year student in the Biochemistry graduate program, Ms. Ortiz excelled accumulating an impressive academic and research credentials.  As a consequence of her successes, she was awarded a position on the Predoctoral Training Grant in the Pharmacological Sciences.  This is an NIH-funded institutional training program that promotes the interdisciplinary training of graduate students.  Ms. Ortiz will carry out her dissertation work in the laboratory of Dr. Kris DeMali and will focus her research efforts on understanding how epithelial cells sense and transmit forces in normal and cancer cells.

Congratulations to the 2017 IDT & Smith-Gehring Graduate Fellows!

Elizabeth Boehm receives 2017 Marion Dave Francis Innovator Award

Wednesday, July 5th, 2017

Dr. Elizabeth Boehm, a 2016 PhD with Dr. Todd Washington, received the 2017 Marion Dave Francis Innovator Award which recognizes a PhD student whose research has demonstrated their singular personal initiative, creativity, and resulting continuous discovery, as exemplified by Dr. Francis.

Dr. Elizabeth Boehm grew up in small farming community in northern Illinois. She attended Winona State University in Winona, MN where she received a Bachelor of Science in Biology. She joined the graduate program in the Biochemistry Department at the University of Iowa in August 2012. She earned a Ph.D. in Biochemistry in August 2016 under the mentorship of Professor Todd Washington. Her research focused on understanding what happens when damaged DNA is replicated during cell division. She developed an experimental approach that allowed her to observe the formation of individual protein complexes in real time. This approach and the new computational tools that she developed for this project will be widely applicable to researchers studying similar protein complexes in many other fields. Currently, Elizabeth is a post-doctoral research associate at Harvard Medical School working with Professor Johannes Walter, a leader in the DNA replication and repair field.

Congratulations, Elizabeth!

Taylor Lab wins FOEDRC Research Day scientific poster awards

Thursday, April 27th, 2017

Adam Rauckhorst (center) & Arpit Sharma (second from right) along with the other FOEDRC poster winners.

Graduate Student Arpit Sharma’s poster entitled “Loss of Skeletal Muscle Mpc1 in Mice Stimulates Fatty Acid Oxidation, Nitrogen Retention, and Leanness,” won the award for best poster in the pre-doctoral category.

Postdoc Adam Rauckhorst’s poster entitled “The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity and hyperglycemia,” tied with three others for the best poster in the post-doctoral/Jr. faculty category.