Link: University of Iowa

Archive for April, 2012

Miles Pufall receives Carver Young Investigator Award

Wednesday, April 25th, 2012

Miles Pufall has been awarded a Carver Young Investigator Award from the Roy J. Carver Charitable Trust for his project, “Understanding glucocorticoid resistance in B cell precursor acute lymphoblastic leukemia.”

This is a three year, $345,000 award to investigate the molecular basis for steroid resistance in acute lymphoblastic leukemia. Dr. Pufall was selected as the sole applicant from the Holden Comprehensive Cancer Center at the University of Iowa. He joins Drs. Lori Wallrath, Adrian Elcock, Todd Washington and Ernesto Fuentes as an early-career recipient of a Carver Trust award.

Madeline Shea renews R01

Friday, April 20th, 2012

Dr. Madeline Shea was recently awarded another four years on her R01, “Molecular Dissection of Calmodulin Domain Functions,” which has been continuously funded since 1998. This grant, which has produced 17 publications thus far, awards Dr. Shea ~$320,000/year for four years to determine how CaM remodels the intracellular C-terminal tail of Nav to provide calcium-mediated switching, laying the ground work for developing future therapies and providing information regarding side-effects of medications taken for epilepsy and other neurological disorders.

Biochemistry Honors students present at Lata Symposium

Thursday, April 19th, 2012

Seven Biochemistry Honors students presented their research yesterday afternoon at the 8th Annual Gene F. Lata Undergraduate Research Symposium. Please join Undergraduate and Honors Advisor, Professor Marc Wold, in congratulating these 2011 graduates and their research mentors for a job well done.

  • Ashley Angell
    Mentor: Kris DeMali
    Tyrosine Phosphorylation of Vinculin Regulates Cell-Matrix Adhesion
  • Chelsea Khaw
    Mentor: Kris DeMali
    The Role of the Β3 Integrin in Melanoma Resistance to Chemotherapy
  • James Min
    Mentor: Joseph Zabner (Pulmonary)
    Organ-specific Expression of a Transgenic Human Lactonase in Drosophila melanogaster
  • Emma Nash
    Mentor: Martha Monick (Internal Medicine)
    Smoking Alters Dicer Expression in Human Alveoler Macrophages
  • Luke Prest
    Mentor: Dan Weeks
    Separating Functional Domains of Cardiac Transcription Factors by Construction of Chimeric Proteins
  • Hyun Soo Ryu
    Mentor: Shahram Khademi
    Mechanisms of Urea Conduction in Urea Channel
  • Austin Stark
    Mentor: Adrian Elcock
    Molecular Simulations of Weak Protein-protein Interactions

Department announces fall 2012 incoming graduate students

Tuesday, April 17th, 2012

The Department of Biochemistry is pleased to announce the results of a successful graduate recruiting season. 10 new graduate students will join the Department, all with great potential. This autumn we will welcome:

Quinn Li (BS, University of California-San Diego, expected 2012)
Emily Malcolm (MS, Georgia Institute of Technology, 2010)
Mark Miller (MS, Stockholm University, expected 2012)
Kyle Powers (BS, University of Illinois-Urbana, expected 2012)
Lalita Oonthonpon (BS, University of Central Arkansas, 2010)
Tingting Duan (Bmed, Shandong University, expected 2012)
Xun (Allison) Chi (BS, Zhejiang University, expected 2012)
Shuxiang Li (MS, Central China Normal University, expected 2012)
Yu-Tsan Liu (MS, National Central University, 2007)
Arpit Sharma (Mtech, Jaypee Institute of Information Technology, expected 2012)

Department fetes Nancy and Earle Stellwagen

Monday, April 16th, 2012

Biochemists gathered on April 14 at Blackstone in Iowa City to celebrate the numerous contributions that Nancy and Earle Stellwagen have made to the Department of Biochemistry, the University of Iowa, and the scientific community during their careers. Charles Brenner read a letter written by Dr. Bob Kelley, a 1984 PhD student of Earl’s, who is nowa Senior Scientist in the Antibody Engineering Department ant Genentech. Dr. Kelly detailed his time in the lab with Ealre, as well as with Nancy, both of whom he praised for their mentorship and scientific rigor. Bryce Plapp read a letter by Dr. Larry Barnes, a former postdoctoral fellow in Earle’s lab, who is currently a Professor at UT Health Science Center. Dr. Barnes stated that his strengths in protein purification/analysis and management skills that he used throughout his career are a direct result of the excellent training provided by the Stellwagens.

The Stellwagens were delighted that their three children, Anne, John and David, returned to IOwa City for the celebration.

Stellwagen Family

Rose Lee wins WISE program award

Tuesday, April 10th, 2012

Congratulations to Rose Lee, a third year medical student working in the Bartlett lab, who received the Women in Science and Engineering (WISE) Program Award at the 13th annual Student Interdisciplinary Health Research Poster Session today for her presentation “Utilizing 3Ds Max Design Programs to Model Mutation-Mediated Actin Dysfunction.” Rose won one of 10 $100 awards.

Xu Liu’s research poster honored during Research Week

Monday, April 9th, 2012

Congratulations to Xu Liu, a graduate student in the Fuentes lab, whose poster was selected as a “most outstanding entry” by the Carver College of Medicine during Research Week 2012. This year’s Research Week (April 2-4, 2012), a joint venture between CCOM, the College of Pharmacy, the College of Public Health, the Institute for Clinical and Translational Science, and the VA Health System, focused on neuroscience. Xu’s poster, entitled “Specificity, Structure, Dynamics and Inhibition of Tiam1 PDZ Domain/Syndecan1 Complex,” was one of three per session selected by CCOM for a $350 prize.

Nancy Stellwagen to receive award

Thursday, April 5th, 2012

Dr. Nancy Stellwagen will be honored in October by the American Electrophoresis Society (AES) for her “significant contributions to electrophoresis and to the AES.” The award will be presented at the Society’s annual meeting.

Walllrath lab featured on the cover of Human Molecular Genetics

Wednesday, April 4th, 2012

Current research from the laboratory of Dr. Lori Wallrath is featured on the cover of the April 1, 2012 issue of Human Molecular Genetics. The accompanying paper by George Dialynas, et al., describes their research done in collaboration with Steven Moore (Pathology) and Katherine Mathews (Pediatrics) on the development of a Drosophila model for LMNA-associated muscular dystrophy. Their studies identified new molecular markers that allow for the diagnosis of specific types of muscular dystrophy. In addition, their findings revealed novel molecular muscle phenotypes in patients with Emery-Dreifuss muscular dystrophy.

Dylan Thiemann honored as a Student Employee of the Year

Tuesday, April 3rd, 2012

Undergraduate Biochemistry major Dylan Thiemann was selected for a Certificate of Appreciation as a Student Employee of the Year. As part of the award, Dylan, along with eight other undergraduates, will have lunch at the President’s home later this month. Congratulations Dylan and thank you for your hard work.